Novel Acinar Metaplastic States Uncovered in Exocrine Pancreas Disease
Katherine J. Aney*, Woo-Jeong Jeong*, Pal Koak, A.W. Ohman, C.H. Nguyen, B.M. Wolpin, J.A. Nowak, Sahar Nissim.
Cellular and Molecular Gastroenterology and Hepatology, 2026 https://doi.org/10.1016/j.jcmgh.2025.101717
Hepatic adaptation to chronic metabolic stress primes tumorigenesis
C.N. Tzouanas*, J.E.S. Shay*, M.S. Sherman*, A.J. Rubin, B.E. Mead, T.T. Dao, J. Tao, B.M. Lehrich, G. Eng, J. Patterson-Fortin, T. Butzlaff, M.D. Mana, K.E. Kolb, C. Walesky, B.J. Pepe-Mooney, C.J. Smith, S.M. Prakadan, M.L. Ramseier, Y.E. Tong, J. Joung, F. Chi, T. McMahon-Skates, C.L. Winston, Woo-Jeong Jeong, Katherine J. Aney, Ethan Chen, Sahar Nissim, F. Zhang, V. Deshpande, S.P. Monga, G.M. Lauer, W. Goessling, Ö.H. Yilmaz, A.K. Shalek.
Cell, 2026 https://doi.org/10.1016/j.cell.2025.11.031
A Novel Approach for Pancreas Transcriptomics Reveals the Cellular Landscape in Homeostasis and Acute Pancreatitis
Katherine J Aney*, Woo-Jeong Jeong*, A.F. Vallejo, C. Burdziak, Ethan Chen, Austin Wang, Pal Koak, K. Wise, K. Jensen, D. Pe'er, S.K. Dougan, L. Martelotto, Sahar Nissim.
Gastroenterology, 2024 https://doi.org/10.1053/j.gastro.2024.01.043
Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer
Sahar Nissim, I. Leshchiner, J.D. Mancias, M.B. Greenblatt, O. Maertens, C.A. Cassa, J.A. Rosenfeld, A.G. Cox, J. Hedgepeth, J.I. Wucherpfennig, A.J. Kim, J.E. Henderson, P. Gonyo, A. Brandt, E. Lorimer, B. Unger, J.W. Prokop, J.R. Heidel, X. Wang, C.I. Ukaegbu, B.C. Jennings, J.A. Paulo, S. Gableske, C.A. Fierke, G. Getz, S.R. Sunyaev, J.W. Harper, K. Cichowski, A.C. Kimmelman, Y. Houvras, S. Syngal, C. Williams, W. Goessling.
Nature Genetics, 2019 https://doi.org/10.1038/s41588-019-0475-y
Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development
Sahar Nissim*, O. Weeks*, J.C. Talbot, J.W. Hedgepeth, J. Wucherpfennig, S. Schatzman-Bone, I. Swinburne, M. Cortes, K. Alexa, S. Megason, T.E. North, S.L. Amacher, W. Goessling.
Developmental Biology, 2016 http://dx.doi.org/10.1016/j.ydbio.2016.07.019
Prostaglandin E2 Regulates Liver versus Pancreas Cell-Fate Decisions and Endodermal Outgrowth
Sahar Nissim, R.I. Sherwood, J. Wucherpfennig, D. Saunders, J.M. Harris, V. Esain, K.J. Carroll, G.M. Frechette, A.J. Kim, K.L. Hwang, C.C. Cutting, S. Elledge, T.E. North, W. Goessling.
Developmental Cell, 2014 http://dx.doi.org/10.1016/j.devcel.2014.01.006
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